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The heterotrimeric kinesin-2 complex interacts with and regulates GLI protein function

GLI transport to the primary cilium and nucleus is required for proper Hedgehog (HH) signaling; however, the mechanisms that mediate these trafficking events are poorly understood. Kinesin-2 motor proteins regulate ciliary transport of cargo, yet their role in GLI protein function remains unexplored...

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Podrobná bibliografie
Vydáno v:J Cell Sci
Hlavní autoři: Carpenter, Brandon S., Barry, Renee L., Verhey, Kristen J., Allen, Benjamin L.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Company of Biologists 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4342584/
https://ncbi.nlm.nih.gov/pubmed/25588831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.162552
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