Roles of Bim in Apoptosis of Normal and Bcr-Abl-Expressing Hematopoietic Progenitors

Bcr-Abl kinase is known to reverse apoptosis of cytokine-dependent cells due to cytokine deprivation, although it has been controversial whether chronic myeloid leukemia (CML) progenitors have the potential to survive under conditions in which there are limited amounts of cytokines. Here we demonstr...

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Bibliographic Details
Main Authors: Kuribara, Ryoko, Honda, Hiroaki, Matsui, Hirotaka, Shinjyo, Tetsuharu, Inukai, Takeshi, Sugita, Kanji, Nakazawa, Shinpei, Hirai, Hisamaru, Ozawa, Keiya, Inaba, Toshiya
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
Transcriptional Regulation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC434248/
https://ncbi.nlm.nih.gov/pubmed/15226421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.14.6172-6183.2004
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