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GlcUAβ1–3Galβ1–3Galβ1–4Xyl(2-O-phosphate) Is the Preferred Substrate for Chondroitin N-Acetylgalactosaminyltransferase-1

A deficiency in chondroitin N-acetylgalactosaminyltransferase-1 (ChGn-1) was previously shown to reduce the number of chondroitin sulfate (CS) chains, leading to skeletal dysplasias in mice, suggesting that ChGn-1 regulates the number of CS chains for normal cartilage development. Recently, we demon...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Izumikawa, Tomomi, Sato, Ban, Mikami, Tadahisa, Tamura, Jun-ichi, Igarashi, Michihiro, Kitagawa, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4342460/
https://ncbi.nlm.nih.gov/pubmed/25568321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.603266
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