The IκB Kinase Complex and NF-κB Act as Master Regulators of Lipopolysaccharide-Induced Gene Expression and Control Subordinate Activation of AP-1

Toll-like receptors (TLRs) recognize conserved products of microbial pathogens to initiate the innate immune response. TLR4 signaling is triggered upon binding of lipopolysaccharides (LPS) from gram-negative bacteria. Using comparative gene expression profiling, we demonstrate a master regulatory ro...

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Hlavní autoři: Krappmann, Daniel, Wegener, Elmar, Sunami, Yoshiaki, Esen, Meral, Thiel, Andreas, Mordmuller, Benjamin, Scheidereit, Claus
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2004
Témata:
Cell Growth and Development
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC434242/
https://ncbi.nlm.nih.gov/pubmed/15226448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.14.6488-6500.2004
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