Npa1p, a Component of Very Early Pre-60S Ribosomal Particles, Associates with a Subset of Small Nucleolar RNPs Required for Peptidyl Transferase Center Modification

We have identified a novel essential nucleolar factor required for the synthesis of 5.8S and 25S rRNAs termed Npa1p. In the absence of Npa1p, the pre-rRNA processing pathway leading to 5.8S and 25S rRNA production is perturbed such that the C2 cleavage within internal transcribed spacer 2 occurs pre...

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Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Dez, Christophe, Froment, Carine, Noaillac-Depeyre, Jacqueline, Monsarrat, Bernard, Caizergues-Ferrer, Michèle, Henry, Yves
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2004
Schlagworte:
Cell and Organelle Structure and Assembly
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC434229/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15226434/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.14.6324-6337.2004
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