Synergistic Activations of REG Iα and REG I β Promoters by IL-6 and Glucocorticoids through JAK/STAT Pathway in Human Pancreatic β Cells

Reg (Regenerating gene) gene was originally isolated from rat regenerating islets and its encoding protein was revealed as an autocrine/paracrine growth factor for β cells. Rat Reg gene is activated in inflammatory conditions for β cell regeneration. In human, although five functional REG family gen...

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Detalles Bibliográficos
Publicado en:J Diabetes Res
Autores principales: Yamauchi, Akiyo, Itaya-Hironaka, Asako, Sakuramoto-Tsuchida, Sumiyo, Takeda, Maiko, Yoshimoto, Kiyomi, Miyaoka, Tomoko, Fujimura, Takanori, Tsujinaka, Hiroki, Tsuchida, Chikatsugu, Ota, Hiroyo, Takasawa, Shin
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4342170/
https://ncbi.nlm.nih.gov/pubmed/25767811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/173058
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