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A mechanism of leading-edge protrusion in the absence of Arp2/3 complex

Cells employ protrusive leading edges to navigate and promote their migration in diverse physiological environments. Classical models of leading-edge protrusion rely on a treadmilling dendritic actin network that undergoes continuous assembly nucleated by the Arp2/3 complex, forming ruffling lamelli...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Suraneni, Praveen, Fogelson, Ben, Rubinstein, Boris, Noguera, Philippe, Volkmann, Niels, Hanein, Dorit, Mogilner, Alex, Li, Rong
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4342026/
https://ncbi.nlm.nih.gov/pubmed/25568333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-07-1250
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