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Weak Force Stalls Protrusion at the Leading Edge of the Lamellipodium

Protrusion, the first step of cell migration, is driven by actin polymerization coupled to adhesion at the cell's leading edge. Polymerization and adhesive forces have been estimated, but the net protrusion force has not been measured accurately. We arrest the leading edge of a moving fish kera...

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Библиографические подробности
Главные авторы: Bohnet, Sophie, Ananthakrishnan, Revathi, Mogilner, Alex, Meister, Jean-Jacques, Verkhovsky, Alexander B.
Формат: Artigo
Язык:Inglês
Опубликовано: Biophysical Society 2006
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1367330/
https://ncbi.nlm.nih.gov/pubmed/16326894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.064600
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