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Morphology of the Lamellipodium and Organization of Actin Filaments at the Leading Edge of Crawling Cells
Lamellipodium extension, incorporating actin filament dynamics and the cell membrane, is simulated in three dimensions. The actin filament network topology and the role of actin-associated proteins such as Arp2/3 are examined. We find that the orientational pattern of the filaments is in accord with...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Biophysical Society
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1366852/ https://ncbi.nlm.nih.gov/pubmed/16085776 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.065383 |
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