Reduction in Subventricular Zone-Derived Olfactory Bulb Neurogenesis in a Rat Model of Huntington’s Disease Is Accompanied by Striatal Invasion of Neuroblasts

Huntington’s disease (HD) is an inherited progressive neurodegenerative disorder caused by an expanded CAG repeat in exon 1 of the huntingtin gene (HTT). The primary neuropathology of HD has been attributed to the preferential degeneration of medium spiny neurons (MSN) in the striatum. Reports on st...

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Publicado en:PLoS One
Autores principales: Kandasamy, Mahesh, Rosskopf, Michael, Wagner, Katrin, Klein, Barbara, Couillard-Despres, Sebastien, Reitsamer, Herbert A., Stephan, Michael, Nguyen, Huu Phuc, Riess, Olaf, Bogdahn, Ulrich, Winkler, Jürgen, von Hörsten, Stephan, Aigner, Ludwig
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4342015/
https://ncbi.nlm.nih.gov/pubmed/25719447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0116069
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