Beneficial Influence of Platelets on Antibiotic Efficacy in an In Vitro Model of Staphylococcus aureus-Induced Endocarditis

Platelets contribute to antimicrobial host defense against infective endocarditis (IE) by releasing platelet microbicidal proteins (PMPs). We investigated the influence of thrombin-stimulated human platelets on the evolution of simulated IE in the presence and absence of vancomycin or nafcillin. Sta...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Mercier, Renee-Claude, Dietz, Robert M., Mazzola, Jory L., Bayer, Arnold S., Yeaman, Michael R.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2004
Soggetti:	Experimental Therapeutics
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC434186/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15215108/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.7.2551-2557.2004
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