Beneficial Influence of Platelets on Antibiotic Efficacy in an In Vitro Model of Staphylococcus aureus-Induced Endocarditis

Platelets contribute to antimicrobial host defense against infective endocarditis (IE) by releasing platelet microbicidal proteins (PMPs). We investigated the influence of thrombin-stimulated human platelets on the evolution of simulated IE in the presence and absence of vancomycin or nafcillin. Sta...

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Bibliographic Details
Main Authors: Mercier, Renee-Claude, Dietz, Robert M., Mazzola, Jory L., Bayer, Arnold S., Yeaman, Michael R.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
Experimental Therapeutics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC434186/
https://ncbi.nlm.nih.gov/pubmed/15215108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.7.2551-2557.2004
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