Multiple-Dose Pharmacokinetics and Safety of a Novel Broad-Spectrum Cephalosporin (BAL5788) in Healthy Volunteers

BAL5788 is the water-soluble prodrug of BAL9141, a novel broad-spectrum cephalosporin with potent bactericidal activity against methicillin-resistant Staphylococcus aureus (MRSA) and penicillin-resistant Streptococcus pneumoniae. Safety and pharmacokinetic data from a multiple-dose study with 16 hea...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Schmitt-Hoffmann, Anne, Nyman, Lars, Roos, Brigitte, Schleimer, Michael, Sauer, Jill, Nashed, Norman, Brown, Thomas, Man, Anthony, Weidekamm, Erhard
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2004
Materias:
Pharmacology
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC434166/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15215111/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.7.2576-2580.2004
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