Candida glabrata erg1 Mutant with Increased Sensitivity to Azoles and to Low Oxygen Tension

A Candida glabrata erg1 (Cgerg1) mutant, CgTn201S, was identified by transposon mutagenesis and by increased fluconazole susceptibility. CgERG1 encodes a 489-amino-acid protein which, on the basis of its homology with Saccharomyces cerevisiae ERG1, is a squalene epoxidase essential for ergosterol sy...

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Autori principali: Tsai, Huei-Fung, Bard, Martin, Izumikawa, Koichi, Krol, Anna A., Sturm, Aaron M., Culbertson, Nicholas T., Pierson, Charles A., Bennett, John E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2004
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Mechanisms of Action: Physiological Effects
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC434157/
https://ncbi.nlm.nih.gov/pubmed/15215098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.7.2483-2489.2004
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