Candida glabrata erg1 Mutant with Increased Sensitivity to Azoles and to Low Oxygen Tension

A Candida glabrata erg1 (Cgerg1) mutant, CgTn201S, was identified by transposon mutagenesis and by increased fluconazole susceptibility. CgERG1 encodes a 489-amino-acid protein which, on the basis of its homology with Saccharomyces cerevisiae ERG1, is a squalene epoxidase essential for ergosterol sy...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Tsai, Huei-Fung, Bard, Martin, Izumikawa, Koichi, Krol, Anna A., Sturm, Aaron M., Culbertson, Nicholas T., Pierson, Charles A., Bennett, John E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2004
Témata:
Mechanisms of Action: Physiological Effects
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC434157/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15215098/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.7.2483-2489.2004
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky