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A novel function of RIP1 in postnatal development and immune homeostasis by protecting against RIP3-dependent necroptosis and FADD-mediated apoptosis

RIP1 is an adaptor kinase originally identified as being able to associate with TNFR1 and Fas, and is later shown to be involved in signaling induced by TLRs. Major signaling pathways regulated by RIP1 include necroptosis, apoptosis, and pro-survival/inflammation NF-κB activation. Previous studies s...

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Bibliografski detalji
Izdano u:Front Cell Dev Biol
Glavni autori: Dowling, John P., Nair, Anirudh, Zhang, Jianke
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4341114/
https://ncbi.nlm.nih.gov/pubmed/25767797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2015.00012
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