Accumulation of Heterochromatin Components on the Terminal Repeat Sequence of Kaposi's Sarcoma-Associated Herpesvirus Mediated by the Latency-Associated Nuclear Antigen

In the latent infection of Kaposi's sarcoma-associated herpesvirus (KSHV), its 160-kb circularized episomal DNA is replicated and maintained in the host nucleus. KSHV latency-associated nuclear antigen (LANA) is a key factor for maintaining viral latency. LANA binds to the terminal repeat (TR)...

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Bibliographic Details
Main Authors: Sakakibara, Shuhei, Ueda, Keiji, Nishimura, Ken, Do, Eunju, Ohsaki, Eriko, Okuno, Toshiomi, Yamanishi, Koichi
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC434099/
https://ncbi.nlm.nih.gov/pubmed/15220403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.14.7299-7310.2004
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