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Accumulation of Heterochromatin Components on the Terminal Repeat Sequence of Kaposi's Sarcoma-Associated Herpesvirus Mediated by the Latency-Associated Nuclear Antigen

In the latent infection of Kaposi's sarcoma-associated herpesvirus (KSHV), its 160-kb circularized episomal DNA is replicated and maintained in the host nucleus. KSHV latency-associated nuclear antigen (LANA) is a key factor for maintaining viral latency. LANA binds to the terminal repeat (TR) DNA o...

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Publicado en:J Virol
Principais autores: Sakakibara, Shuhei, Ueda, Keiji, Nishimura, Ken, Do, Eunju, Ohsaki, Eriko, Okuno, Toshiomi, Yamanishi, Koichi
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2004
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC434099/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15220403/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.14.7299-7310.2004
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