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Histidine 352 (His(352)) and Tryptophan 355 (Trp(355)) Are Essential for Flax UGT74S1 Glucosylation Activity toward Secoisolariciresinol

Flax secoisolariciresinol diglucoside (SDG) lignan is a natural phytoestrogen for which a positive role in metabolic diseases is emerging. Until recently however, much less was known about SDG and its monoglucoside (SMG) biosynthesis. Lately, flax UGT74S1 was identified and characterized as an enzym...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Ghose, Kaushik, McCallum, Jason, Sweeney-Nixon, Marva, Fofana, Bourlaye
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340967/
https://ncbi.nlm.nih.gov/pubmed/25714779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0116248
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