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Histidine 352 (His(352)) and Tryptophan 355 (Trp(355)) Are Essential for Flax UGT74S1 Glucosylation Activity toward Secoisolariciresinol

Flax secoisolariciresinol diglucoside (SDG) lignan is a natural phytoestrogen for which a positive role in metabolic diseases is emerging. Until recently however, much less was known about SDG and its monoglucoside (SMG) biosynthesis. Lately, flax UGT74S1 was identified and characterized as an enzym...

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Опубликовано в: :PLoS One
Главные авторы: Ghose, Kaushik, McCallum, Jason, Sweeney-Nixon, Marva, Fofana, Bourlaye
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340967/
https://ncbi.nlm.nih.gov/pubmed/25714779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0116248
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