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Safety and Immunogenicity of an Intranasal Sendai Virus-Based Human Parainfluenza Virus Type 1 Vaccine in 3- to 6-Year-Old Children

Human parainfluenza virus type 1 (hPIV-1) is the most common cause of laryngotracheobronchitis (croup), resulting in tens of thousands of hospitalizations each year in the United States alone. No licensed vaccine is yet available. We have developed murine PIV-1 (Sendai virus [SeV]) as a live Jenneri...

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Detalles Bibliográficos
Publicado en:Clin Vaccine Immunol
Autores principales: Adderson, Elisabeth, Branum, Kristen, Sealy, Robert E., Jones, Bart G., Surman, Sherri L., Penkert, Rhiannon, Freiden, Pamela, Slobod, Karen S., Gaur, Aditya H., Hayden, Randall T., Allison, Kim, Howlett, Nanna, Utech, Jill, Allay, Jim, Knight, James, Sleep, Susan, Meagher, Michael M., Russell, Charles J., Portner, Allen, Hurwitz, Julia L.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340902/
https://ncbi.nlm.nih.gov/pubmed/25552633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00618-14
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