Sendai virus recombinant vaccine expressing a secreted, unconstrained respiratory syncytial virus fusion protein protects against RSV in cotton rats

The respiratory syncytial virus (RSV) is responsible for as many as 199000 annual deaths worldwide. Currently, there is no standard treatment for RSV disease and no vaccine. Sendai virus (SeV) is an attractive pediatric vaccine candidate because it elicits robust and long-lasting virus-specific B ce...

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Detalhes bibliográficos
Publicado no:Int Immunol
Main Authors: Zhan, Xiaoyan, Slobod, Karen S., Jones, Bart G., Sealy, Robert E., Takimoto, Toru, Boyd, Kelli, Surman, Sherri, Russell, Charles J., Portner, Allen, Hurwitz, Julia L.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4406265/
https://ncbi.nlm.nih.gov/pubmed/25477211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxu107
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