Safety and Immunogenicity of an Intranasal Sendai Virus-Based Human Parainfluenza Virus Type 1 Vaccine in 3- to 6-Year-Old Children

Human parainfluenza virus type 1 (hPIV-1) is the most common cause of laryngotracheobronchitis (croup), resulting in tens of thousands of hospitalizations each year in the United States alone. No licensed vaccine is yet available. We have developed murine PIV-1 (Sendai virus [SeV]) as a live Jenneri...

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Detalhes bibliográficos
Publicado no:Clin Vaccine Immunol
Main Authors: Adderson, Elisabeth, Branum, Kristen, Sealy, Robert E., Jones, Bart G., Surman, Sherri L., Penkert, Rhiannon, Freiden, Pamela, Slobod, Karen S., Gaur, Aditya H., Hayden, Randall T., Allison, Kim, Howlett, Nanna, Utech, Jill, Allay, Jim, Knight, James, Sleep, Susan, Meagher, Michael M., Russell, Charles J., Portner, Allen, Hurwitz, Julia L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340902/
https://ncbi.nlm.nih.gov/pubmed/25552633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00618-14
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