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Intrinsic Obstacles to Human Immunodeficiency Virus Type 1 Coreceptor Switching
The natural evolution of human immunodeficiency virus type 1 infection often includes a switch in coreceptor preference late in infection from CCR5 to CXCR4, a change associated with expanded target cell range and worsened clinical prognosis. Why coreceptor switching takes so long is puzzling, since...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2004
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC434079/ https://ncbi.nlm.nih.gov/pubmed/15220431 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.14.7565-7574.2004 |
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