Intrinsic Obstacles to Human Immunodeficiency Virus Type 1 Coreceptor Switching

The natural evolution of human immunodeficiency virus type 1 infection often includes a switch in coreceptor preference late in infection from CCR5 to CXCR4, a change associated with expanded target cell range and worsened clinical prognosis. Why coreceptor switching takes so long is puzzling, since...

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Bibliografiske detaljer

Udgivet i:	J Virol
Principais autores:	Pastore, Cristina, Ramos, Alejandra, Mosier, Donald E.
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 2004
Fag:	Pathogenesis and Immunity
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC434079/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15220431/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.14.7565-7574.2004
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