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Famine versus feast: understanding the metabolism of tumors in vivo

To fuel unregulated proliferation, cancer cells alter metabolism to support macromolecule biosynthesis. Cell culture studies have revealed how different oncogenic mutations and nutrients impact metabolism. Glucose and glutamine are the primary fuels used in vitro; however, recent studies have sugges...

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Publicado en:Trends Biochem Sci
Autores principales: Mayers, Jared R., Vander Heiden, Matthew G.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340757/
https://ncbi.nlm.nih.gov/pubmed/25639751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2015.01.004
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