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Famine versus feast: understanding the metabolism of tumors in vivo

To fuel unregulated proliferation, cancer cells alter metabolism to support macromolecule biosynthesis. Cell culture studies have revealed how different oncogenic mutations and nutrients impact metabolism. Glucose and glutamine are the primary fuels used in vitro; however, recent studies have sugges...

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Detalhes bibliográficos
Publicado no:Trends Biochem Sci
Main Authors: Mayers, Jared R., Vander Heiden, Matthew G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340757/
https://ncbi.nlm.nih.gov/pubmed/25639751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2015.01.004
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