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Famine versus feast: understanding the metabolism of tumors in vivo

To fuel unregulated proliferation, cancer cells alter metabolism to support macromolecule biosynthesis. Cell culture studies have revealed how different oncogenic mutations and nutrients impact metabolism. Glucose and glutamine are the primary fuels used in vitro; however, recent studies have sugges...

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Bibliografische gegevens
Gepubliceerd in:Trends Biochem Sci
Hoofdauteurs: Mayers, Jared R., Vander Heiden, Matthew G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340757/
https://ncbi.nlm.nih.gov/pubmed/25639751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2015.01.004
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