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Famine versus feast: understanding the metabolism of tumors in vivo

To fuel unregulated proliferation, cancer cells alter metabolism to support macromolecule biosynthesis. Cell culture studies have revealed how different oncogenic mutations and nutrients impact metabolism. Glucose and glutamine are the primary fuels used in vitro; however, recent studies have sugges...

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Publicat a:Trends Biochem Sci
Autors principals: Mayers, Jared R., Vander Heiden, Matthew G.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340757/
https://ncbi.nlm.nih.gov/pubmed/25639751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2015.01.004
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