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Dysbiosis-induced intestinal inflammation activates TNFRI and mediates alcoholic liver disease in mice

Intestinal barrier dysfunction is an important contributor to alcoholic liver disease. Translocated microbial products trigger an inflammatory response in the liver and contribute to steatohepatitis. Our aim was to investigate mechanisms of barrier disruption following chronic alcohol feeding. A Lie...

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Detalhes bibliográficos
Publicado no:Hepatology
Main Authors: Chen, Peng, Stärkel, Peter, Turner, Jerrold R., Ho, Samuel B., Schnabl, Bernd
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340725/
https://ncbi.nlm.nih.gov/pubmed/25251280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.27489
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