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Voriconazole, an Antifungal Triazol That Causes Visual Side Effects, Is an Inhibitor of TRPM1 and TRPM3 Channels

PURPOSE. Administration of voriconazole, an antifungal triazole, causes transient visual disturbances in patients and attenuates the b-wave of the ERG. We sought to identify the retinal target of voriconazole underlying the effect on the ERG b-wave. METHODS. Electroretinograms were recorded from mic...

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Bibliographic Details
Published in:Invest Ophthalmol Vis Sci
Main Authors: Xiong, Wei-Hong, Brown, R. Lane, Reed, Brian, Burke, Neal S., Duvoisin, Robert M., Morgans, Catherine W.
Format: Artigo
Language:Inglês
Published: The Association for Research in Vision and Ophthalmology 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340431/
https://ncbi.nlm.nih.gov/pubmed/25650413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.14-15270
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