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Voriconazole, an Antifungal Triazol That Causes Visual Side Effects, Is an Inhibitor of TRPM1 and TRPM3 Channels

PURPOSE. Administration of voriconazole, an antifungal triazole, causes transient visual disturbances in patients and attenuates the b-wave of the ERG. We sought to identify the retinal target of voriconazole underlying the effect on the ERG b-wave. METHODS. Electroretinograms were recorded from mic...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Xiong, Wei-Hong, Brown, R. Lane, Reed, Brian, Burke, Neal S., Duvoisin, Robert M., Morgans, Catherine W.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340431/
https://ncbi.nlm.nih.gov/pubmed/25650413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.14-15270
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