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A Novel Isoform of Met Receptor Tyrosine Kinase Blocks Hepatocyte Growth Factor/Met Signaling and Stimulates Skeletal Muscle Cell Differentiation

Hepatocyte growth factor (HGF) and its receptor, Met, regulate skeletal muscle differentiation. In the present study, we identified a novel alternatively spliced isoform of Met lacking exon 13 (designated Δ13Met), which is expressed mainly in human skeletal muscle. Alternative splicing yielded a tru...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Biol Chem
Main Authors: Park, Minseon, Lee, Bok-Soon, Jeon, Soung-Hoo, Nam, Hyun-Ja, Lee, Gwang, Kim, Chul-Ho, Cho, Hyeseong, Lee, Jae-Ho
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2015
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340422/
https://ncbi.nlm.nih.gov/pubmed/25471370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.596957
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