Choline Kinase β Mutant Mice Exhibit Reduced Phosphocholine, Elevated Osteoclast Activity, and Low Bone Mass

The maintenance of bone homeostasis requires tight coupling between bone-forming osteoblasts and bone-resorbing osteoclasts. However, the precise molecular mechanism(s) underlying the differentiation and activities of these specialized cells are still largely unknown. Here, we identify choline kinas...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Kular, Jasreen, Tickner, Jennifer C., Pavlos, Nathan J., Viola, Helena M., Abel, Tamara, Lim, Bay Sie, Yang, Xiaohong, Chen, Honghui, Cook, Robert, Hool, Livia C., Zheng, Ming Hao, Xu, Jiake
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340415/
https://ncbi.nlm.nih.gov/pubmed/25451916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.567966
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