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Modification of CETP function by changing its substrate preference: a new paradigm for CETP drug design
We previously determined that hamster cholesteryl ester transfer protein (CETP), unlike human CETP, promotes a novel one-way transfer of TG from VLDL to HDL, causing HDL to gain lipid. We hypothesize that this nonreciprocal lipid transfer activity arises from the usually high TG/cholesteryl ester (C...
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| Veröffentlicht in: | J Lipid Res |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The American Society for Biochemistry and Molecular Biology
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4340308/ https://ncbi.nlm.nih.gov/pubmed/25616437 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M056333 |
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