New paradigms and tools in drug design for pain and addiction

New modalities providing safe and effective treatment of pain, especially prolonged pathological pain, have not appeared despite much effort. In this mini-review/overview we suggest that new paradigms of drug design are required to counter the underlying changes that occur in the nervous system that...

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Détails bibliographiques
Auteurs principaux: Hruby, Victor J., Porreca, Frank, Yamamura, Henry I., Tollin, Gordon, Agnes, Richard S., Lee, Yeon Sun, Cai, Minying, Alves, Isabel, Cowell, Scott, Varga, Eva, Davis, Peg, Salamon, Zdzislaw, Roeske, William, Vanderah, Todd, Lai, Josephine
Format: Artigo
Langue:Inglês
Publié: Springer-Verlag 2006
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1764851/
https://ncbi.nlm.nih.gov/pubmed/17025262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/aapsj080353
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