A lipidomic screen of hyperglycemia-treated HRECs links 12/15-Lipoxygenase to microvascular dysfunction during diabetic retinopathy via NADPH oxidase

Retinal hyperpermeability and subsequent macular edema is a cardinal feature of early diabetic retinopathy (DR). Here, we investigated the role of bioactive lipid metabolites, in particular 12/15-lipoxygenase (LOX)-derived metabolites, in this process. LC/MS lipidomic screen of human retinal endothe...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:J Lipid Res
Glavni autori: Ibrahim, Ahmed S., Elshafey, Sally, Sellak, Hassan, Hussein, Khaled A., El-Sherbiny, Mohamed, Abdelsaid, Mohammed, Rizk, Nasser, Beasley, Selina, Tawfik, Amany M., Smith, Sylvia B., Al-Shabrawey, Mohamed
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Biochemistry and Molecular Biology 2015
Teme:
Research Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340307/
https://ncbi.nlm.nih.gov/pubmed/25598081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M056069
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items