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Analysis of ssDNA Gaps and DSBs in Genetically Unstable Yeast Cultures

DNA replication defects are an underlying cause of genome instability, which could stem from alterations in replication intermediates such as extensive single-stranded DNA (ssDNA). Under replication stress, ssDNA is a precursor of the ultimate double-strand breaks (DSBs). Indeed, mutations that rend...

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Foilsithe in:Methods Mol Biol
Main Authors: Peng, Jie, Raghuraman, M.K., Feng, Wenyi
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2014
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340247/
https://ncbi.nlm.nih.gov/pubmed/24906332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-0888-2_27
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