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Analysis of ssDNA Gaps and DSBs in Genetically Unstable Yeast Cultures
DNA replication defects are an underlying cause of genome instability, which could stem from alterations in replication intermediates such as extensive single-stranded DNA (ssDNA). Under replication stress, ssDNA is a precursor of the ultimate double-strand breaks (DSBs). Indeed, mutations that rend...
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| Publicado no: | Methods Mol Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4340247/ https://ncbi.nlm.nih.gov/pubmed/24906332 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-0888-2_27 |
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