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Thiostrepton Inhibition of Initiation Factor 1 Activity in Polypeptide Chain Initiation in Escherichia coli

Thiostrepton, a peptide antibiotic, inhibits the GTP-dependent 70S initiation complex formation (as measured by binding of fMet-tRNA to ribosomes and concomitant hydrolysis of GTP) only when initiation factor 1 is present to permit catalytic recycling of initiation factor 2 in the initiation reactio...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Sarkar, Probir, Stringer, Evan A., Maitra, Umadas
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 1974
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Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC434024/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4612536/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.71.12.4986
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