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Beyond Peptides and mAbs - Current Status and Future Perspectives for Biotherapeutics with Novel Constructs

Biotherapeutics are attractive anti-cancer agents due to their high specificity and limited toxicity compared to conventional small molecules. Antibodies are widely used in cancer therapy, either directly or conjugated to a cytotoxic payload. Peptide therapies, though not as prevalent, have been uti...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Clin Pharmacol
Hauptverfasser: AlDeghaither, Dalal, Smaglo, Brandon G, Weiner, Louis M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340091/
https://ncbi.nlm.nih.gov/pubmed/25707963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcph.407
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