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Viable Deletion Mutants of Simian Virus 40: Selective Isolation by Means of a Restriction Endonuclease from Hemophilus parainfluenzae

Resistance of simian virus 40 (SV40) DNA to cleavage by Hemophilus parainfluenzae II (HpaII) restriction endonuclease has been used as a positive, in vitro selection for mutants lacking the one HpaII endonuclease-cleavage site of wild-type SV40 DNA. Each of 10 viable mutants isolated by this procedu...

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Detalhes bibliográficos
Main Authors: Mertz, Janet E., Berg, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: 1974
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC434002/
https://ncbi.nlm.nih.gov/pubmed/4373732
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