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Extension of the Lifespan of Cultured Normal Human Diploid Cells by Vitamin E

Inclusion of vitamin E (DL-α-tocopherol) in the culture medium for human diploid cells greatly prolongs their in vitro lifespan. The addition of 100 μg of DL-α-tocopherol per ml of medium has allowed us to culture WI-38 cells for more than 100 population doublings to date. (These cells normally have...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Packer, Lester, Smith, James R.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1974
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433977/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4531015/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.71.12.4763
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