Analysis of the Link between the Redox State and Enzymatic Activity of the HtrA (DegP) Protein from Escherichia coli

Bacterial HtrAs are proteases engaged in extracytoplasmic activities during stressful conditions and pathogenesis. A model prokaryotic HtrA (HtrA/DegP from Escherichia coli) requires activation to cleave its substrates efficiently. In the inactive state of the enzyme, one of the regulatory loops, te...

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Bibliographic Details
Published in:PLoS One
Main Authors: Koper, Tomasz, Polit, Agnieszka, Sobiecka-Szkatula, Anna, Wegrzyn, Katarzyna, Scire, Andrea, Figaj, Donata, Kadzinski, Leszek, Zarzecka, Urszula, Zurawa-Janicka, Dorota, Banecki, Bogdan, Lesner, Adam, Tanfani, Fabio, Lipinska, Barbara, Skorko-Glonek, Joanna
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4339722/
https://ncbi.nlm.nih.gov/pubmed/25710793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0117413
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