Analysis of the Link between the Redox State and Enzymatic Activity of the HtrA (DegP) Protein from Escherichia coli

Bacterial HtrAs are proteases engaged in extracytoplasmic activities during stressful conditions and pathogenesis. A model prokaryotic HtrA (HtrA/DegP from Escherichia coli) requires activation to cleave its substrates efficiently. In the inactive state of the enzyme, one of the regulatory loops, te...

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Veröffentlicht in:PLoS One
Hauptverfasser: Koper, Tomasz, Polit, Agnieszka, Sobiecka-Szkatula, Anna, Wegrzyn, Katarzyna, Scire, Andrea, Figaj, Donata, Kadzinski, Leszek, Zarzecka, Urszula, Zurawa-Janicka, Dorota, Banecki, Bogdan, Lesner, Adam, Tanfani, Fabio, Lipinska, Barbara, Skorko-Glonek, Joanna
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4339722/
https://ncbi.nlm.nih.gov/pubmed/25710793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0117413
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