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Measuring Affinity Constants of 1,450 Monoclonal Antibodies to Peptide Targets with a Microarray-based Label-Free Assay Platform

Monoclonal antibodies (mAbs) are major reagents for research and clinical diagnosis. For their inherently high specificities to intended antigen targets and thus low toxicity in general, they are pursued as one of the major classes of new drugs. Yet binding properties of most monoclonal antibodies a...

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Dades bibliogràfiques
Publicat a:J Immunol Methods
Autors principals: Landry, J. P., Ke, Yaohuang, Yu, Guo-Liang, Zhu, X. D.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4339518/
https://ncbi.nlm.nih.gov/pubmed/25536073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2014.12.011
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