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Measuring Affinity Constants of 1,450 Monoclonal Antibodies to Peptide Targets with a Microarray-based Label-Free Assay Platform

Monoclonal antibodies (mAbs) are major reagents for research and clinical diagnosis. For their inherently high specificities to intended antigen targets and thus low toxicity in general, they are pursued as one of the major classes of new drugs. Yet binding properties of most monoclonal antibodies a...

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Detalhes bibliográficos
Publicado no:J Immunol Methods
Main Authors: Landry, J. P., Ke, Yaohuang, Yu, Guo-Liang, Zhu, X. D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4339518/
https://ncbi.nlm.nih.gov/pubmed/25536073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2014.12.011
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