Persistent Pain Maintains Morphine-Seeking Behavior after Morphine Withdrawal through Reduced MeCP2 Repression of Glua1 in Rat Central Amygdala

As long-term opioids are increasingly used for control of chronic pain, how pain affects the rewarding effect of opioids and hence risk of prescription opioid misuse and abuse remains a healthcare concern and a challenging issue in current pain management. In this study, using a rat model of morphin...

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Foilsithe in:J Neurosci
Main Authors: Hou, Yuan-Yuan, Cai, You-Qing, Pan, Zhizhong Z.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Society for Neuroscience 2015
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Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4339367/
https://ncbi.nlm.nih.gov/pubmed/25716866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3453-14.2015
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