The Chemical and Biological Effects of cis-Dichlorodiammineplatinum (II), an Antitumor Agent, on DNA
cis-Dichlorodiammineplatinum (II) binds irreversibly to the bases in DNA; the amount of platinum complex bound can be determined from changes in the ultraviolet absorption spectrum. As the ratio of platinum to phosphate is increased, an increasing inactivation of bacterial transforming DNA is observ...
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| Опубликовано в:: | Proc Natl Acad Sci U S A |
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| Главный автор: | |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
1974
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433918/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4548188/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.71.11.4519 |
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