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USP45 deubiquitylase controls ERCC1–XPF endonuclease-mediated DNA damage responses
Reversible protein ubiquitylation plays important roles in various processes including DNA repair. Here, we identify the deubiquitylase USP45 as a critical DNA repair regulator. USP45 associates with ERCC1, a subunit of the DNA repair endonuclease XPF–ERCC1, via a short acidic motif outside of the U...
Enregistré dans:
| Publié dans: | EMBO J |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BlackWell Publishing Ltd
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4339120/ https://ncbi.nlm.nih.gov/pubmed/25538220 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201489184 |
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