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USP45 deubiquitylase controls ERCC1–XPF endonuclease-mediated DNA damage responses

Reversible protein ubiquitylation plays important roles in various processes including DNA repair. Here, we identify the deubiquitylase USP45 as a critical DNA repair regulator. USP45 associates with ERCC1, a subunit of the DNA repair endonuclease XPF–ERCC1, via a short acidic motif outside of the U...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:EMBO J
Prif Awduron: Perez-Oliva, Ana B, Lachaud, Christophe, Szyniarowski, Piotr, Muñoz, Ivan, Macartney, Thomas, Hickson, Ian, Rouse, John, Alessi, Dario R
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BlackWell Publishing Ltd 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4339120/
https://ncbi.nlm.nih.gov/pubmed/25538220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201489184
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