Cuprizone does not induce CNS demyelination in nonhuman primates

Cognitive decline is a common symptom in multiple sclerosis patients, with profound effects on the quality of life. A nonhuman primate model of multiple sclerosis would be best suited to test the effects of demyelination on complex cognitive functions such as learning and reasoning. Cuprizone has be...

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Bibliographische Detailangaben
Veröffentlicht in:Ann Clin Transl Neurol
Hauptverfasser: Chen, Zhihong, Chen, Jacqueline T, Johnson, Matthew, Gossman, Zachary C, Hendrickson, Megan, Sakaie, Ken, Martinez-Rubio, Clarissa, Gale, John T, Trapp, Bruce D
Format: Artigo
Sprache:Inglês
Veröffentlicht: BlackWell Publishing Ltd 2015
Schlagworte:
Brief Communications
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338961/
https://ncbi.nlm.nih.gov/pubmed/25750925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.159
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