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Deficiency of Akt1, but not Akt2, attenuates the development of pulmonary hypertension
Pulmonary vascular remodeling, mainly attributable to enhanced pulmonary arterial smooth muscle cell proliferation and migration, is a major cause for elevated pulmonary vascular resistance and pulmonary arterial pressure in patients with pulmonary hypertension. The signaling cascade through Akt, co...
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Publicado no: | Am J Physiol Lung Cell Mol Physiol |
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Main Authors: | , , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Physiological Society
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4338938/ https://ncbi.nlm.nih.gov/pubmed/25416384 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00242.2014 |
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