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Hemin Causes Lung Microvascular Endothelial Barrier Dysfunction by Necroptotic Cell Death
Hemin, the oxidized prosthetic moiety of hemoglobin, has been implicated in the pathogenesis of acute chest syndrome in patients with sickle cell disease by virtue of its endothelial-activating properties. In this study, we examined whether hemin can cause lung microvascular endothelial barrier dysf...
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| Pubblicato in: | Am J Respir Cell Mol Biol |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Thoracic Society
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5625223/ https://ncbi.nlm.nih.gov/pubmed/28421813 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2016-0287OC |
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